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Live

June 27, 2013 | USA 9:00 AM EDT, 8:00 AM CDT, 6:00 AM PDT, 14:00BST 

Speaker: Dr. Dierk Roessner, Senior Application Specialist, Wyatt Technology Europe

Characterization of macromolecules is a key and crucial application when working with research and development of Biopharmaceuticals as well as academic research. During this Webinar which is co-hosting between Wyatt Technology Europe and Agilent you will learn about methods to analyze macromolecules in complex samples using Field Flow Fractionation (FFF) coupled to MALS (Multi Angle Light Scattering). The FFF and MALS is fully integrated with the Agilent 1260 Bio-inert HPLC. FFF is an FDA accepted orthogal method to SEC and offers the following benefits:

  • FFF separation works in an open channel without a stationary phase, is gentle (very little shear forces) and works under native conditions
  • FFF separates from one nm size up to a few microns, therefore method of choice for samples with colloidal components (protein aggregates, liposomes, micelles, viruses, colloidal drug carriers, etc.)
 

 

 
 
Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution. These tools include: in-line multi-angle static light scattering, high-throughput dynamic light scattering, differential refractometry, electrophoretic mobility, differential viscosity, field flow fractionation and automated composition gradients.