Light scattering provides a powerful suite of techniques for biophysical screening and characterization in the pursuit of a stable yet efficacious biotherapeutic formulation. In this webinar we will explore various analytical tools employing multi-angle static light scattering (MALS) dynamic light scattering (DLS) and electrophoretic mobility phase-analysis light scattering (EM-PALS):

• High-throughput screening (HTS) DLS, performed directly in microwell plates, to qualify buffer conditions for aggregation, colloidal stability, thermal stability and viscosity 
• SEC-MALS and FFF-MALS for quantifying aggregates small and large in a stability course study 
• EM-PALS for determining net charge
• CG-MALS for characterizing self-association/self-interaction and protein-excipient interactions at moderate to high protein concentration, as well as protein-target binding 

• Orthogonal Analytical Approaches
• Wyatt Columns for Light Scattering
• Protein Conjugates

• Principles of Field Flow Fractionation

• Biomolecular Interactions 
• High Protein Concentration Interactions

• High Throughput Dynamic Light Scattering
• DLS for Proteins, Polymers and Nanoparticles
• Combining Size and Molar Mass Measurements

• Automated Measurements of Zeta Potential
• Charge Analysis of Biomolecules and Nanoparticles