Wyatt Technology

Drug Delivery Nanoparticles Illuminated: the Light Scattering Toolkit-Part 1, Batch Measurements

 

Presented Live: December 24, 2015

Nanoparticle drug delivery systems (nanoDDS) are among the most promising avenues for effective treatment of many disorders, accomplished by the targeted release of chemotherapeutics, peptides, siRNA or genetic material. Some of the key analytical challenges faced by nanoDDS researchers and drug product developers include the determination of accurate, high-resolution size distributions; reliable and non-perturbative assessments of particle conformation, stability and payload; and rapid, effective formulation screens.

This webinar describes a suite of analytical techniques, all based on light scattering, that addresses many of these challenges. We review light scattering fundamentals, then present examples illustrating how Wyatt's unique light scattering instrumentation enhances productivity in the course of studying and developing nanoDDS including liposomes, VLPs, polymeric micelles, polymer-encapsulated therapeutics and nanogels.

 

 

   

For essential macromolecular and nanoparticle characterization—The Solution is Light™

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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.



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