Proteins

Proteins

# Description Download
1

Aggregation of proteins

 Multi-Angle Light Scattering - Aggregation of proteins
2

Reverse-phase protein characterization

 Multi-Angle Light Scattering - Reverse-phase protein characterization
3

Wheat proteins by reversed phase chromatography

 Multi-Angle Light Scattering - Wheat proteins by reversed phase chromatography
4

Protein modifications using PEGylation to change the drug-delivery properties of a protein.

 Multi-Angle Light Scattering - Protein modifications using PEGylation to change the drug-delivery properties of a protein
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PEGylated protein characterization with the number of PEG attachments!

 Multi-Angle Light Scattering - PEGylated protein characterization with the number of PEG attachments!
6

Micro-batch characterization of proteins

 Multi-Angle Light Scattering - Micro-batch characterization of proteins
7

Aggregation as a function of concentration of proteins.

 Multi-Angle Light Scattering - Aggregation as a function of concentration of proteins.
8

Peptides and proteins showing the power of the miniDAWN for low molar mass characterization of biopolymers.

 Multi-Angle Light Scattering - Peptides and proteins showing the power of the miniDAWN for low molar mass characterization of biopolymers.
9

Hemoglobin--One of the building blocks of life! This note examines the elution properties of this protein and how different they are from more "conventional" proteins.

 Multi-Angle Light Scattering - Hemoglobin--One of the building blocks of life! This note examines the elution properties of this protein and how different they are from more conventional proteins.
10

Lens proteins--a complex protein which exhibits conformational changes across the molar mass distribution.

 Multi-Angle Light Scattering - Lens proteins--a complex protein which exhibits conformational changes across the molar mass distribution.
11

Gelatins--Used in everything from food thickening agents to photographic film substrates, gelatins can be analyzed successfully and absolutely with SEC-MALS, as this note shows.

 Multi-Angle Light Scattering - Gelatins--Used in everything from food thickening agents to photographic film substrates, gelatins can be analyzed successfully and absolutely with SEC-MALS, as this note shows.
12

Protein-Protein Interactions--Scientists working at Pfizer's Central Research Laboratory show that the DAWN is an invaluable tool for the development of a scale-up purification protocol.

 Multi-Angle Light Scattering - Protein-Protein Interactions--Scientists working at Pfizer's Central Research Laboratory show that the DAWN is an invaluable tool for the development of a scale-up purification protocol.
13

How antibodies that are developed to be powerful drugs can bind specifically to a target molecule or cell.

 Multi Angle Static Light Scattering - How antibodies that are developed to be powerful drugs can bind specifically to a target molecule or cell.
14

This note concerns the use of an infrared (IR) laser in characterizing a protein that fluoresces at the red wavelength, but did not fluoresce at the longer IR wavelength.

 Multi Angle Static Light Scattering - This note concerns the use of an infrared (IR) laser in characterizing a protein that fluoresces at the red wavelength, but did not fluoresce at the longer IR wavelength
15

It discusses the application of MALS-QELS interfacing to enable absolute molar mass and size determinations from 1nm to 500nm. In this note we use BSA, as well as a glycoprotein sample to show the range of masses and sizes we can characterize by both static and dynamic light scattering.

 Multi Angle Static Light Scattering - It discusses the application of MALS-QELS interfacing to enable absolute molar mass and size determinations from 1nm to 500nm. In this note we use BSA, as well as a glycoprotein sample to show the range of masses and sizes we can characterize by both static and dynamic light scattering.
16

Proteins can elute at radically different times depending on their structure, yet simple column chromatography misses this completely. By adding a MALS with the WyattQELS accessory, the subtleties of proteins may be studied.

 Multi Angle Static Light Scattering - Proteins can elute at radically different times depending on their structure, yet simple column chromatography misses this completely. By adding a MALS with the WyattQELS accessory, the subtleties of proteins may be studied.
17

To obtain absolute molar masses of heat shock proteins at different temperatures, multi-angle light scattering (MALS) detection was used following SEC.

 Multi Angle Static Light Scattering - To obtain absolute molar masses of heat shock proteins at different temperatures, multi-angle light scattering (MALS) detection was used following SEC.
18

Membrane protein is generally soluble only in the presence of micelles; thus, it is very difficult to characterize the oligomerization state of the membrane protein in a lipid-containing solvent. In this application note we demonstrate the use of multi-angle light scattering (MALS) detection in combination with UV absorption and differential refractive index (DRI) detection to determine the molar masses (MM) of both the core protein and the entire protein-lipid complex.

 Multi Angle Static Light Scattering - Membrane protein is generally soluble only in the presence of micelles; thus, it is very difficult to characterize the oligomerization state of the membrane protein in a lipid-containing solvent. In this application note we demonstrate the use of multi-angle light scattering (MALS) detection in combination with UV absorption and differential refractive index (DRI) detection to determine the molar masses (MM) of both the core protein and the entire protein-lipid complex.
19

Calcium Storage Protein Calsequestrin

 Multi Angle Static Light Scattering - Calcium Storage Protein Calsequestrin
20

Hemoglobin Unfolding & Aggregation

 Multi Angle Static Light Scattering - Hemoglobin Unfolding & Aggregation
21

Refractive index based determination of detergent concentration and its application to the study of membrane proteins

 Multi Angle Static Light Scattering - Refractive index based determination of detergent concentration and its application to the study of membrane proteins
22

Ribosomal Subunits in Protein Biosynthesis

 Multi Angle Static Light Scattering - Ribosomal Subunits in Protein Biosynthesis
23

Binding Stoichiometry of an Antibody Fragment

 Multi Angle Static Light Scattering - Binding Stoichiometry of an Antibody Fragment
24

Kinase Fragment

 Multi Angle Static Light Scattering - Kinase Fragment
25

Automated, Online Second Virial Coefficient (A2) Measurements

 Multi Angle Static Light Scattering - Automated, Online Second Virial Coefficient (A2) Measurements
26

Stoichiometry of Lysin Holoenzyme

 Multi Angle Static Light Scattering - Stoichiometry of Lysin Holoenzyme
27

Low Molecular Weight Lens Peptides and Changes in the Oligomeric Organization of αB-crystallin

 Multi Angle Static Light Scattering - Low Molecular Weight Lens Peptides and Changes in the Oligomeric Organization of αB-crystallin
28

Molecular weight distribution of gluten proteins analysed by MALS

 Multi Angle Static Light Scattering - Molecular weight distribution of gluten proteins analysed by MALS
29

Characterization of Spongiform Encephalopathies

 Multi Angle Static Light Scattering - Characterization of Spongiform Encephalopathies
30 Multi-Angle and Dynamic Light Scattering - Role Of Oligomeric Size In Chaperone Function Of αB-Crystallin Multi-Angle and Dynamic Light Scattering - Role Of Oligomeric Size In Chaperone Function Of αB-Crystallin
31 Soluble Protein-Protein Associations Multi Angle Static Light Scattering - Soluble Protein-Protein Associations
32 Biophysical Properties of Crystallin Aggregates Multi Angle Static Light Scattering - Biophysical Properties of Crystallin Aggregates
33 Novel Malaria Vaccine Candidates Multi Angle Static Light Scattering - Novel Malaria Vaccine Candidates
34 Protein Aggregation States Multi Angle Static Light Scattering - Protein Aggregation States
35 Purification of the Rab11-FIP2 Complex Multi Angle Static Light Scattering - Purification of the Rab11-FIP2 Complex
36 Rapid, Automated Molecular Characterization Using a Binary HPLC pump Multi Angle Static Light Scattering - Molecular_Characterization

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Wyatt Technology is the world leader in providing the most advanced macromolecular and nanoparticle characterization tools. These instruments and software may be used to determine the absolute molecular weight and or size of macromolecules and nanoparticles and include: multi-angle light scattering, dynamic light scattering, high through-put dynamic light scattering, field flow fractionation, refractive index and viscometry detection.