The finest, most versatile light scattering instrument for reliable electrophoretic mobility measurements of proteins, particles, and macromolecules.
Wyatt Technology’s Möbiuζ (Mobius) is the first and only light scattering instrument that makes reliable, reproducible, and non-destructive electrophoretic mobility measurements of macromolecules as small as 1 nm, under dilute solution conditions. The Möbiuζ (Mobius) was designed with the goal of measuring the mobility and the hydrodynamic radius of precious protein samples, without perturbing these fragile species. By overcoming the challenges presented by these delicate nanoparticles, the technological advancements embodied in the Möbiuζ (Mobius) offer unique capabilities for traditional applications. Electrical charge is a fundamental property of all macromolecules. In colloidal suspensions, the formulation stability depends critically on the amount of charge developed at the interfaces between particles and their solvent. For most biomolecules—like proteins—electrostatic interactions exercise a profound influence on their conformation, function, and efficacy. Practically speaking, electrophoretic mobility has been the most popular and widely accepted proxy for the molecular charge and interfacial potential, also known as the zeta potential.
Light Source: 50 mW diode pumped solid state (DPSS) single-longitudinal- mode laser
Laser Wavelength: 532 nm, other wavelengths available upon request
Laser Lifetime: > 10,000 hours
Detectors: 30 detector channels for multi-angle detection
Detector type: Multi-element photodiode array for mobility measurements;
Single photon counting module for QELS option
Cell Options: Reusable PEEK flow cell with optical quality windows for
aqueous and organic solvents
Disposable COC* cell for aqueous and polar organic solvents
Wyatt Technology is the world leader in providing the most advanced macromolecular and nanoparticle characterization tools. These instruments and software may be used to determine the absolute molecular weight and or size of macromolecules and nanoparticles and include: multi-angle light scattering, dynamic light scattering, high through-put dynamic light scattering, field flow fractionation, refractive index, zeta potential and viscometry detection.
