Speed up size and stability screening with high-throughput dynamic light scattering
Revolutionize your biotherapeutic and nanoparticle development with high- throughput dynamic light scattering (HT-DLS) and the automated DynaPro® Plate Reader. The DynaPro excels at high-throughput sizing and screening of biopharmaceutical and nanoparticle formulations to enable novel workflows that simply would not be possible with other DLS instruments.
The DynaPro Plate Reader
offers a complete solution in a standard well plate
- Discover small-molecule and peptide drugs
- Develop stable biopharmaceuticals
- Formulate nanoparticles
- Optimize protein buffers
- Characterize gene vectors
Obtain the Complete Attribute Landscape
- Size and size distributions (rh)
- Molar mass (Mw)
- Aggregation and stability indicators (Tonset, Tm, Tagg, kD, A2)
- Viscosity
- Solubility
- Titer/ particle concentration
Fast, Easy, Accurate
- Uses industry-standard 96, 384 or 1,536 microwell plates
- Sample volume as low as 4 μL
- User friendly experiment design in Dynamics
- As sensitive as a cuvette-based DLS
- First and only A2 and Mw in a plate
- Film- or oil-based evaporation seal
- Measure from 4 ºC to 85 ºC
- Infrared wavelength not susceptible to fluorescence
- 21 CFR Part 11 compliant software
Design High-throughput Experiments
Advantages
Explore content-rich screening data and tackle comprehensive DLS experiments you never thought possible.
Weeks of Experiments in Just Hours
Biologics: Thermal and Colloidal Stability
The DynaPro Plate Reader performs high-throughput screening of biotherapeutic candidates, to determine multiple properties of a plateful of candidates and formulations. Shown to the right is the analysis of monoclonal antibodies (mAbs) for thermal stability.
