Upcoming Live Webinars

Advances in automated dynamic light scattering characterization and zeta potential of macromolecules and nanoparticles using the DynaPro™ ZetaStar™

Join us for a webinar on Tuesday, October 10 at 8:00 AM PDT | 11:00 AM EDT | 17:00 CEST

Size, polydispersity, and charge or zeta potential are important attributes of a particle or macromolecule because they uniquely describe the ID, state, and stability of a sample. Equally important to measuring these properties is conducting the measurement in high salt solutions, that mimic physiological conditions. Unfortunately, these measurements tend to be cumbersome and time-consuming. However, this doesn’t need to be the case, in this webinar, we will introduce the capability for increasing efficiency through automated, unattended screening of a large range of sample and buffer conditions. This is especially relevant for scientists working to develop and optimize formulations of lipid nanoparticles, metal nanoparticles and complex proteins.

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Shining Light on AAVs: Using Light Scattering Technologies to Solve Challenges in Characterization

Join us for a webinar on Wednesday, October 18 at 8:00 AM PDT | 11:00 AM EDT | 17:00 CEST

With the rising clinical and commercial successes of AAV-based gene therapies, there is an ever-growing demand for robust, platform analytical technologies that can help ensure better product quality, safety, and efficacy. Size exclusion chromatography (SEC) and Field Flow Fractionation (FFF), coupled with multi-angle light scattering technologies (MALS), are rapidly emerging as transformative technologies for rapid and accurate characterization of AAV samples. Critical Quality Attributes (CQAs) such as capsid titer, genome titer, empty/full, % aggregation and purity of various AAV serotypes can all be obtained in a single measurement. This multi-attribute approach dramatically reduces operational costs and reduces drug development timelines.

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Optimizing development and release efficiency of protein, AAV and LNP therapies using Multi-Attribute Quantification (MAQ) Light Scattering

Join us for a webinar on Wednesday, November 1 at 8:00 AM PST | 11:00 AM EST | 17:00 CET

Light scattering (LS) techniques, both dynamic LS (DLS) and multi-angle static LS (MALS), have been used as important biophysical characterization and quantification tools for biopharmaceuticals for the past decades. For proteins, DLS, especially in the plate reader format, is used to screen for aggregation presence and propensity and formulation conditions, whereas MALS combined with size exclusion chromatography (SEC) is employed throughout the development cycle of the protein therapeutics.

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Determination of critical product parameters for proteins from research to production

Join us for a webinar on Wednesday, November 8 at 8:00 AM PST | 11:00 AM EST | 17:00 CET

During this webinar the diversity of various light scattering techniques for characterizing a wide range of protein samples and their applicability in pharmaceutical research will be shared.

We will start by highlighting the potential of dynamic light scattering (DLS) as a tool for rapid and straightforward aggregate detection, as well as its value in executing extensive formulation studies and predicting stability.

This will be followed by applications of multi-angle light scattering (SEC-MALS and FFF-MALS), showcasing its ability to provide absolute molecular weight, oligomerization, and conjugate analyses.

We will conclude with an introduction to real-time MALS, offering real-time insights and enabling direct process influence on attributes such as molar mass, size, and particle concentration.

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IgM protein

Recent Webinars

Previous webinars may be viewed in our Webinar Library. The following recent webinars are now available:

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