Upcoming Live Webinars
Characterizing Polymers and Polymer Aggregates Using
SEC-MALS and Batch-Mode MALS
Join us for a webinar on January 27, 8:00 AM PST | 11:00 AM EST | 17:00 CET
Multi-angle light scattering (MALS) remains a critical tool for characterization of polymers. In combination with separation by size-exclusion chromatography (SEC), MALS enables determination of molar mass distributions without relying on reference standards, making it invaluable for the analysis of polymers for which such standards do not exist, including novel homopolymers, block copolymers, and polymers with complex topologies. Beyond characterization of single macromolecules, batch-mode MALS can be used to analyze polymer assemblies that cannot survive fractionation conditions.
In this webinar we briefly review the theory and technology of MALS, then present specific applications in the characterization of homopolymers, block copolymers, lightly crosslinked polymers and polymer micelles.
Therapeutic Proteins in Biological Fluids:
Size Characterization Using AF4 with
Fluorescence and SPR Detection
Join us for a webinar on February 24, 8:00 AM PST | 11:00 AM EST | 17:00 CET
The analysis of aggregates of therapeutic proteins is crucial to ensure efficacy and patient safety. Typically, the analysis is performed in the finished formulation to ensure that aggregates are not present. An important question is, however, what happens to therapeutic proteins, with regard to oligomerization and aggregation, after they have been administrated intravenously.
This webinar features a demonstration of the separation of whole blood, plasma, and serum using asymmetric-flow field-flow fractionation (AF4) with a minimum of sample pre-treatment. The analysis of therapeutic antibodies in blood plasma using AF4 with fluorescence and surface plasmon resonance (SPR) detection is demonstrated in pre-clinical research with further potential for use in clinical trials, following implementation of appropriate quality systems. The results show the suitability and strength of AF4 for blood protein analysis and opens new important routes for the analysis and characterization of therapeutic proteins in blood.
Previous webinars may be viewed in our Webinar Library. The following recent webinars are now available:
John Champagne, Ph.D., Wyatt Technology
January 19, 2021
December 8 & 10, 2020
Measuring physical properties of liposomes and LNPs for RNA delivery with multidetector asymmetric-flow field-flow fractionation
Fanny Caputo, Ph.D., SINTEF, and Christoph Johann, Ph.D., Wyatt Technology
December 15, 2020
Rational use of dynamic light scattering for the characterization of cytokines, bispecific antibody fusion proteins and binary antibody mixtures
Hristo Svilenov, Ph.D., Technical University of Munich, and Sophia Kenrick, Ph.D., Wyatt Technology
November 17, 2020
Christoph Johann, Ph.D., and Chris Deng, Ph.D., Wyatt Technology
October 27, 2020
October 22, 2020
Daniel Some, Ph.D., Wyatt Technology
September 22, 2020
French webinar: Real-Time MALS: A Breakthrough in Process Analytical Technology for Nanoparticles, Biopharmaceuticals and Polymers
Thierry Azoulay, Wyatt Technology
September 22, 2020
Lionel Rouzic, Ingénieur Applications
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