Upcoming Live Webinars
Characterizing Polymers and Polymer Aggregates Using
SEC-MALS and Batch-Mode MALS
Join us for a webinar on January 27, 8:00 AM PST | 11:00 AM EST | 17:00 CET
Multi-angle light scattering (MALS) remains a critical tool for characterization of polymers. In combination with separation by size-exclusion chromatography (SEC), MALS enables determination of molar mass distributions without relying on reference standards, making it invaluable for the analysis of polymers for which such standards do not exist, including novel homopolymers, block copolymers, and polymers with complex topologies. Beyond characterization of single macromolecules, batch-mode MALS can be used to analyze polymer assemblies that cannot survive fractionation conditions.
In this webinar we briefly review the theory and technology of MALS, then present specific applications in the characterization of homopolymers, block copolymers, lightly crosslinked polymers and polymer micelles.
Therapeutic Proteins in Biological Fluids:
Size Characterization Using AF4 with
Fluorescence and SPR Detection
Join us for a webinar on February 24, 8:00 AM PST | 11:00 AM EST | 17:00 CET
The analysis of aggregates of therapeutic proteins is crucial to ensure efficacy and patient safety. Typically, the analysis is performed in the finished formulation to ensure that aggregates are not present. An important question is, however, what happens to therapeutic proteins, with regard to oligomerization and aggregation, after they have been administrated intravenously.
This webinar features a demonstration of the separation of whole blood, plasma, and serum using asymmetric-flow field-flow fractionation (AF4) with a minimum of sample pre-treatment. The analysis of therapeutic antibodies in blood plasma using AF4 with fluorescence and surface plasmon resonance (SPR) detection is demonstrated in pre-clinical research with further potential for use in clinical trials, following implementation of appropriate quality systems. The results show the suitability and strength of AF4 for blood protein analysis and opens new important routes for the analysis and characterization of therapeutic proteins in blood.
Recent Webinars
Previous webinars may be viewed in our Webinar Library. The following recent webinars are now available:
Quantify Viral Vector Attributes with Light Scattering
John Champagne, Ph.D., Wyatt Technology
January 19, 2021Virtual User Meeting – Screening for stability: Characterizing formulations with DLS
Wyatt Technology
December 8 & 10, 2020Measuring physical properties of liposomes and LNPs for RNA delivery with multidetector asymmetric-flow field-flow fractionation
Fanny Caputo, Ph.D., SINTEF, and Christoph Johann, Ph.D., Wyatt Technology
December 15, 2020Rational use of dynamic light scattering for the characterization of cytokines, bispecific antibody fusion proteins and binary antibody mixtures
Hristo Svilenov, Ph.D., Technical University of Munich, and Sophia Kenrick, Ph.D., Wyatt Technology
November 17, 2020A breakthrough development in FFF-MALS – raising performance and usability to a new level
Christoph Johann, Ph.D., and Chris Deng, Ph.D., Wyatt Technology
October 27, 2020Virtual User Meeting – New Methods and Applications in Field Flow Fractionation
Wyatt Technology
October 22, 2020Real-Time Process Analytics and Control for Vaccine Nanoparticles and Macromolecules
Daniel Some, Ph.D., Wyatt Technology
September 22, 2020French webinar: Real-Time MALS: A Breakthrough in Process Analytical Technology for Nanoparticles, Biopharmaceuticals and Polymers
Thierry Azoulay, Wyatt Technology
September 2020Virtual User Meeting – Polymers, Light Scattering, Viscometry
Wyatt Technology
September 22, 2020Version Française du webinar: Adeno-associated Viruses and Viral Vectors
Lionel Rouzic, Ingénieur Applications
September 2020
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