AN2601: Liposome Structure and Concentration Determined by FFF-MALS-DLS

Conformation of Liposomes

During drug nanocarrier research and development as well as production quality control, it is of great importance to monitor liposome size distributions accurately while also verifying drug encapsulation.

FFF-MALS-DLS, consisting of field-flow fractionation (FFF) combined with multi-angle light scattering (MALS) and dynamic light scattering (DLS), is a powerful tool for characterizing the size, concentration and structure of large nanoparticle ensembles.