E-book: Optimizing the Analysis of Viral Vectors with Light Scattering

To ensure the safety and efficacy of a viral vector-based gene therapy, it is crucial to identify, characterize, understand, and monitor critical quality attributes (CQAs) such as particle size, concentration, the payload (e.g., ratio of empty to full capsids), and degree of aggregation. Light scattering offers a direct physical means of measuring these quantities.