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Multi-Detector SEC Characterization of Polymer Architectures


Presented Live: July 30, 2019

Presented by: Judit Puskas, Ph.D., Ohio State University (OSU)

This webcast will discuss the analysis of polymer architectures—including linear random coil, branched (star, random, hyperbranched), and ring structures—using high-resolution, multi-detector size-exclusion chromatography (SEC). Multi-detector SEC combines macromolecular separation by SEC with online multi-angle light scattering (MALS), differential refractometry (dRI), ultraviolet (UV) absorbance, differential viscosity and quasi-elastic light scattering (QELS, a.k.a. dynamic light scattering, DLS). The rich data afforded by this system provides detailed characterization of polymer molecular structure and composition.


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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.

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