Unveil the Power of Dynamic Light Scattering (DLS) with Wyatt Technology
Accurate, reliable characterization of nanoparticles and macromolecules
Dynamic Light Scattering (DLS) is a critical technique for determining the size distribution and stability of particles in solution. With Wyatt Technology's advanced DLS detectors, researchers and scientists can achieve precise measurements of hydrodynamic radii ranging from sub-nanometer to micrometer scales.

Why choose Wyatt's DLS solutions?
Exceptional Sensitivity and Precision
Wyatt Technology is the recognized leader in light scattering instrumentation. Our DLS instruments provide unparalleled sensitivity and resolution.
User-Friendly Interface
Wyatt's intuitive software ensures that both novice and experienced users can quickly set up experiments and analyze data.
Versatile Applications
Suitable for proteins, polymers, nanoparticles, and other colloids. Our DLS instruments are essential tools in biopharmaceutical research, materials science, and quality control.
Dynamic Light Scattering Instruments

DynaPro™ Plate Reader​
Automated DLS and static light scattering (SLS) measured directly in standard microwell plate.

DynaPro™ NanoStar™​
Cuvette-based DLS/SLS instrument with optional (multi-angle light scattering) MALS integration​.

DynaPro™ ZetaStar™
Fast & automated DLS/SLS and electrophoretic light scattering (ELS) instrument. Optional MALS integration.​​​
Features and Benefits
- Excellent size range​
- Microliter sample usage​
- Adaptive measurement
- Automated data quality assessment
- Streamlined user interface
- Programmable temperature control
- 21CFR Part 11 compliance
DynaPro DLS/SLS Plate Reader
High-throughput, automated dynamic light scattering

The DynaPro DLS/SLS Plate Reader offers DLS measurements in industry-standard microwell plates. It collects data in one day that would otherwise take weeks. Load and run multiple samples simultaneously with a multichannel pipetter or integrate with a liquid handling system.​

Tiny drop, massive data​
Obtain up to 5 parameters (size, polydispersity, particle concentration, Tonset,
Tagg) with just 4µL of samples.
Standard plate, exceptional data​​
Get exceptional data with industry-standard 96, 384, and 1536 well plates.
Enhance your entire workflow​
Rapid screening in candidate selection, formulation development, and quality control aggregation detection.
DynaPro NanoStar
Traditional dynamic light scattering instrument, with MALS connectivity

The DynaPro NanoStar DLS/SLS instrument uniquely combines two optimized 90° detections channels: one for DLS and one for SLS. The NanoStar instrument offers easy walk-up operation with an intuitive touchscreen app, delivering robust, accurate measurements using just 2 µL of sample.​
Results with just a tap ​
The intuitive touch interface guides users to top-quality light scattering measurements with virtually no training.
Wide cuvette selection​​​
Choose from top-quality 2 µL reusable quartz cuvette, 4 µL disposable to generic plastic cuvettes.​
MALS integration​​
Connects via optical fiber to ​DAWN™ MALS instrument line for on-line DLS measurement.
DynaPro ZetaStar
Walk-up or automated measurements of DLS/SLS and ELS​
​

The DynaPro ZetaStar DLS/SLS/ELS instrument includes all the capabilities of the NanoStar instrument, with an added ELS detector and automation compatibility. The ZetaStar instrument delivers both increased sensitivity and up to 10x faster (DLS and ELS) measurements compared to traditional methods.​​
Fast and Intuitive​
Measure particle concentration, size, and zeta potential up to 10x faster than other competitors with just 65 µL.
ELS in native buffer​​​
Obtain size and zeta potential in formulation buffer without dilution with the aid of an Arc™ pump and autosampler or the Atlas™ module.
Hands-free automation​
Combine the ZetaStar instrument with an Arc pump and autosampler for unattended measurements of dozens of samples.​
2-in-1 with MALS integration​ ​

The ZetaStar and NanoStar instruments can be fiber-coupled to the DAWN online multi-angle light scattering (MALS) instrument line, positioned downstream from a liquid chromatography system, providing high-resolution size distributions.​
Applications
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| DynaPro Plate Reader | DynaPro NanoStar | DynaPro ZetaStar | |
|---|---|---|---|
| Description | Automated DLS and SLS measured directly in standard microwell plate | Cuvette-based DLS/SLS instrument with optional MALS integration | Fast & automated DLS/SLS and ELS instrument; optional MALS integration |
| Size and Polydispersity | |||
| Molar Mass | |||
| Particle Concentration | |||
| Zeta Potential | |||
| Tonset of Aggregation | |||
| Colloidal Stability (A2, kD) | |||
| Thermal Stability | |||
| Turbidity | |||
| Viscosity | |||
| MALS Integration | |||
| Automation |














