DAWN™ - MALS Instrument
Absolute molar mass and size characterization
The world’s most advanced Multi-Angle Light Scattering (MALS) instrument for absolute characterization of proteins, polymers and nanoparticles.
The DAWN offers the highest sensitivity, the widest range of molecular weight, size and concentration, and the largest selection of configurations and optional modules for enhanced capabilities.

Premier MALS
The DAWN may be positioned downstream of all types of standard GPC, HPLC or FPLC systems for analysis of molar mass and size distributions, and derivatives such as conjugation and conformation analyses, all included in the ASTRA™ data collection and analysis software.
MALS means more information
Obtain absolute molar mass, size, and aggregation measurement. Integrate any LC systems and detectors to perform advanced analyses, such as determining the empty/full ratio of viral vectors, DAR of conjugated proteins, encapsulation efficiency of LNPs, or polymer branching analyses.
Superior technology
The DAWN instrument is constructed to achieve the highest sensitivity and the broadest detection range. It goes beyond having high angle counts. Its precise optics virtually eliminate all stray light. The two adaptive laser monitoring systems and automated cell cleaning modules ensure a dependable measurement.
It’s a partnership
We strive to provide the best instruments, best training, and the best support possible so that you can focus on your product.

Suitable from beginning to the end of your workflow:
- Research and Development
- Structure Characterization
- Formulation & Stability
- Product Development
- Quality Control
Wide-ranging Utility
The DAWN exceptional detection range covers a broad range of applications from peptides, proteins, synthetic and natural polymers, to vesicles, emulsions, and nanoparticles.




Featured Customers
Xiang Li
China National Institute of Food and Drug Control
The Wyatt detector plays a key role in the quality analysis of proteins, nucleic acids, protein complexes, and gene therapy drugs.
Sharee Adams-Hall
Pfizer, Inc.
Wyatt’s SEC-MALS analytical instruments and software determine multiple critical quality attributes, and have proven essential for supporting process development of complex biotherapeutics such as vaccines and AAV.
Nada Lallous, Ph.D.
University of British Columbia
Wyatt instruments have been invaluable in our research, aiding us in assessing protein quality, characterizing oligomeric states, and identifying critical molecular interactions.
Were are here to help
Contact us for a free consultation
Contact info:
Wyatt Technology Corporation
6330 Hollister Ave
Santa Barbara, CA 93117 USA
Phone: +1 (805) 681-9009
E-mail: info@wyatt.com
Thank you.



