Wyatt Technology



High performance thermostat for FFF and SEC/GPC: 4 to 90°C

THERMOS[PRO] is a combined heating and cooling unit used to hold separation channels for field-flow fractionation as well as hollow fiber modules and SEC/GPC columns. Constant measurement conditions reduce fluctuations and enable more comparable results. THERMOS[PRO] supports measurements at temperatures from 4 to 90°C. Combined with an Eclipse DualTec or Eclipse AF4 with switching option, all of these techniques can be run under precise temperature control. THERMOS[PRO] can be operated as a "standalone" device via an intuitive control panel or fully integrated into the Eclipse® software solution. 

Multiple separation devices at the same time

With a large effective internal volume of 19 liters, THERMOS[PRO] is the first heating and cooling device to hold all Eclipse® series separation channels and also SEC columns up to a length of 450 mm. Due to the innovative holder system, six 450 mm columns plus six pre-columns and an Eclipse® flat channel and Eclipse® HF5 cartridge can be mounted simultaneously. 

Aqueous and organic version
All THERMOS[PRO] models feature a leakage detection as well as overheating/freezing protection. Furthermore, all organic versions are equipped with two redundantly acting vapor sensors. The user is notified visually and audibly in case of a fault. THERMOS[PRO] is always in contact with the other integrated devices on the hardware level and switches to standby mode automatically if third-party components fail. 
Aqueous and Organic Version - Thermos

Professional measurement setup

The capillaries are managed neatly by a system which can be adapted to the specific requirements so that the workstation is always tidy and therefore safe. The four laterally mounted multi-port pass-throughs offer a maximum degree of flexibility when connecting the THERMOS[PRO] to the existing HPLC and detector infrastructure. 

Increase output and quality

Depending on the sample-properties the separation method can be more specifically adjusted leading to an improvement in quality or quantity of the measurements. In many cases aggregation and entanglement issues of the samples are strongly temperature dependent and can be decreased significantly by an appropriate choice of ambient temperature. 

Clear view at any time

The interior is lit using modern LED technology so that the user can always monitor the separation experiments from the outside without interrupting the heating/cooling process by opening the door. This is essential in particular during FFF experiments. 

Maintenance-free hardware

No consequential costs to expect because THERMOS[PRO] has no wear and tear parts. 

THERMOS[PRO] can be operated by :

  • Agilent OpenLAB CDS ChemStation
  • Thermo Chromeleon 6.8 & 7.2
  • Thermos[PRO] Control Center (stand-alone application)


  • Temperature range: 4 to 90°C (at room temperature 20°C)
  • Aqueous and organic version
  • Effective internal volume: 19 L
  • Dimensions (w/h/d): 270x692x378 mm
  • Interior space (w/h/d): 220x488x246 mm
  • Weight: 20 kg
  • Supply voltage: 100–240 V AC / 50–60 Hz
  • Power rating: 300 W



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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.

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