Wyatt Technology

WISH Injection Module

WISH Injection Module

The Wyatt Injection System High-Pressure (WISH™) is ideal for SEC-MALS without an autosampler. Used like a standard injector valve, upon injection the WISH generates an autoinject contact-closure signal to the DAWN® or miniDAWN® MALS detector, read by ASTRA to trigger data collection.

More WISHes

That's not all the WISH can do! It may also be used with an Optilab refractive index detector for the determination of dn/dc values in the "flowing batch" (i.e., flowing through a flow cell, but unfractionated) mode, or even to calibrate your Optilab against NaCl standards.

And more: the WISH facilitates other types of flowing batch measurements such as Zimm Plot analysis (MALS vs concentration, to determine average solution molar mass and size, and second virial coefficients) with a MALS detector.

The centerpiece of the WISH is a specially-designed injector module that makes flowing batch measurements a breeze. Connect your syringe pump or HPLC pump to the injector inlet, and follow up with your Wyatt MALS or RI instrument for a simple and super-stable measurement platform.

The WISH operates at pressures up to 7000 psi (480 bar) and is compatible with common organic and aqueous solvents.*

The WISH Kit includes a 1 mL injection loop (standard, other sizes available upon request), a handful of syringes to help get you started, and an autoinject cable for connection to a Wyatt instrument.

If you are a current US or Canadian Wyatt Technology customer, you can purchase the WISH online. Visit the Wyatt Technology Store today!


*Wetted materials are 316 stainless steel, alumina ceramic and Vespel. Vespel is not compatible with dimethyl formamide (DMF) or sodium hydroxide. If these materials are not compatible with your solutions, please contact info@wyatt.com regarding a special version of this accessory incorporating titanium and Tefzel in place of 316 stainless steel and Vespel.


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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.

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