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    Preparation, Measurement, and Fractionation of Monodisperse Single Wall Carbon Nanotubes

    presented by Dr. Philip Wyatt, Chief Executive Officer
    December 19, 2015 | 11:10 - 11:30 AM

    The many extant and growing applications of single wall carbon nanotubes (SWCNT) suggest strongly that care must be exercised to insure that each such application includes a physical description of the nanotubes used as well as a specification of the properties best suited for the application being studied. One of the most important features of these nanotubes is their length. Assuming that they are not aggregated, it remains to establish for subsequent use that their lengths are known accurately and that each sample is comprised of nanotubes of the same length, i.e. the sample is monodisperse. Using Wahlund chromatographic separation (also known as A4F), traditionally prepared SWCNT samples are fractionated and each fraction sized. Using newly developed analytical techniques, the length of such fractions may be determined during the separation process. Specific size subsets then may be segregated as they elute insuring, thereby, that the nanotube samples to be used are monodisperse. Preparation protocols may be differentiated and quantified, for example, on the basis of the differential size distributions they yield.

    Place: Honolulu, HI
    For more info: Pacifichem 2015 Meeting


    CHI's PepTalk 2016

    Molar mass, size and interactions: light scattering tools for essential biophysical characterization

    Presented by Dr. Wafa Hassouneh, Applications Scientist
    Thursday, January 21, 2016 3:05 PM

    Biophysical techniques based on static and dynamic light scattering address many of the key analytical challenges in biotherapeutic research and development, from early candidate selection through scale-up, formulation, characterization and comparability studies. This seminar will review light scattering technology and instrumentation, then present select examples illustrating how Wyatt's light scattering solutions facilitate rapid and effective development of biologics including mAbs, ADCs, PEGylated and other proteins.

    Exhibitor RibbonVisit us at Booth #413

    Place: San Diego, CA
    For more info: 2016 PepTalk Annual Conference


    WCBP 2016

    At-line and off: The Light Scattering Toolkit for Essential Biophysical Characterization

    Presented by Dr. Daniel Some, Director of Marketing & Principal Scientist
    Wednesday, January 27, 2016 10:20 AM

    From aggregates to conjugates and peptides to polysaccharides, light scattering detectors combine with a variety of sample delivery systems to provide a comprehensive suite of biophysical characterization tools. The latest addition to the toolkit, the µDAWN, adds multi-angle light scattering capabilities to UHPLC for enhanced resolution, speed and productivity in absolute molar mass determination. This seminar presents an overview of instrumentation and examples of the tasks relevant to well-characterized biopharmaceuticals that may be accomplished with these tools, with a look at potential for use in-line and at-line on the production floor.

    Exhibitor RibbonVisit us at Booth #26

    Place: Palm Court Room, Mayflower Hotel, Washington, DC
    For more info: 2016 WCBP Conference


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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.

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