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  • AAPS Annual Meeting and Exposition 2015

    Essential characterization from peptides to nanoparticles: High-throughput sizing and formulation by dynamic light scattering

    Presented by Dr. John Champagne, Northeast Regional Manager & Senior Applications Scientist
    Monday | October 26, 2015 | 10:00 AM

    Dynamic light scattering (DLS) offers rapid assessment of protein and nanoparticle formulations for aggregation and stability, but standard DLS is not conducive to analysis of many excipients and buffer conditions. The DynaPro Plate Reader II performs DLS in-situ in standard microwell plates, compressing weeks’ worth of DLS measurements into hours.

    Exhibitor RibbonVisit us at Booth #2129

    Place: Orlando, FL
    For more info: 2015 AAPS Annual Meeting



    Preparation, Measurement, and Fractionation of Monodisperse Single Wall Carbon Nanotubes

    presented by Dr. Philip Wyatt, Chief Executive Officer
    December 19, 2015 | 11:10 - 11:30 AM

    The many extant and growing applications of single wall carbon nanotubes (SWCNT) suggest strongly that care must be exercised to insure that each such application includes a physical description of the nanotubes used as well as a specification of the properties best suited for the application being studied. One of the most important features of these nanotubes is their length. Assuming that they are not aggregated, it remains to establish for subsequent use that their lengths are known accurately and that each sample is comprised of nanotubes of the same length, i.e. the sample is monodisperse. Using Wahlund chromatographic separation (also known as A4F), traditionally prepared SWCNT samples are fractionated and each fraction sized. Using newly developed analytical techniques, the length of such fractions may be determined during the separation process. Specific size subsets then may be segregated as they elute insuring, thereby, that the nanotube samples to be used are monodisperse. Preparation protocols may be differentiated and quantified, for example, on the basis of the differential size distributions they yield.

    Place: Honolulu, HI
    For more info: Pacifichem 2015 Meeting


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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.

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