Wyatt Technology

Notes by Technique

 

  • multi-angle light scattering

    SEC-MALS

    Absolute molar mass and size distributions of macromolecules in solution, combining a DAWN® or miniDAWN™ multi-angle static light scattering (MALS) instrument with size exclusion chromatography (SEC/GPC).

  • multi-angle light scattering

    μSEC-MALS

    Absolute molar mass and size distributions of macromolecules in solution, combining a μDAWN™ multi-angle static light scattering (MALS) instrument with ultra-high-performance size exclusion chromatography (UHPLC-SEC).

  • field-flow fractionation

    FFF-MALS

    Separation and characterization of macromolecules and nanoparticles without chromatographic columns, using the Eclipse™ field-flow fractionation systems.

  • composition-gradient light scattering for biomolecular interactions

    CG-MALS

    Biomolecular interactions using the Calypso® composition-gradient system.

  • multi-angle light scattering

    Batch MALS

    Time-dependent and other unfractionated measurements of average molar mass and size by multi-angle static light scattering (MALS).

  • dynamic light scattering

    DLS

    Cuvette and microwell-plate based sizing with the DynaPro® Plate Reader II and DynaPro NanoStar.

  • electrophoretic light scattering zeta potential

    ELS

    Electrophoretic mobility, zeta potential and molecular charge with the Möbiuζ®.

  • intrinsic viscosity

    SEC-IV

    Polymer size, conformation and molar mass by intrinsic viscosity

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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.



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