Wyatt Technology

On-line Differential Refractometers for HPLC and UHPLC

  • Optilab T-rEX

    Optilab T-rEX

    An on-line differential refractometer with EXtended range for universal concentration and dn/dc measurements.

    The Optilab T-rEX provides both exquisite sensitivity and 50 times the dynamic range of every other RI detector available. It is the only on-line detector offering temperature control both above and below ambient, as well as measurement of the absolute refractive index of solvents. A high concentration version measures protein concentration up to 180 mg/mL.

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  • Optilab UT-rEX

    Optilab UT-rEX

    Universal concentration measurement for use with all UHPLC systems.

    The Optilab UT-rEX is a unique Refractive Index detector that offers high sensitivity and 50 times the dynamic range of every other UHPLC RI detector. Like the Optilab T-rEX, it offers temperature control both above and below ambient, as well as measurement of the absolute refractive index of solvents.

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Feature Comparison

Capabilities Optilab T-rEX Optilab T-rEX
(High Concentration)
Optilab UT-rEX
   
Differential Refractive Index
Range -0.0047 – +0.0047 RIU -0.0026 – +0.034 RIU -0.0047 – +0.0047 RIU
Peak-to-Peak Noise ± 7.5 x 10-10 RIU ± 1.5 x 10-9 RIU ± 1.5 x 10-9 RIU
Dynamic Range 12,000,000:1 23,000,000:1 6,000,000:1
Acquisition Period 0.1 – 5 seconds/sample 0.1 – 5 seconds/sample 0.04 – 5 seconds/sample
   
Absolute Refractive Index      
Range 1.2 – 1.8 RIU 1.2 – 1.8 RIU 1.2 – 1.8 RIU
Sensitivity ± 0.002 RIU ± 0.002 RIU ± 0.002 RIU
   
Fluidics      
Band Broadening < 20 µL < 20 µL < 4 µL
Flow Cell & Inlet Tubing Volume 51.4 µL 51.4 µL 13.9 µL
   
Sample Temperature 4°C – 65°C 4°C – 65°C 4°C – 65°C

 

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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.



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