User Meetings
2019 Upcoming User Meetings
- Boston AAV User Meeting & Workshop: November 19, 2019 in Woburn, MA
- Philadelphia AAV User Meetings & Workshop: November 22, 2019 in Philadelphia, PA
AAV Workshop: An introduction to the characterization of AAV by light scattering
Adeno-associated virus (AAV) is an attractive delivery vehicle in gene therapy attributed to its mild immune response and ability to deliver the therapeutic genome into a wide range of host cells. To ensure the safety and efficacy of the viral vector-based drug product, it is essential to implement robust and reliable characterization tools throughout the production and manufacturing process. In this presentation, we will discuss a size exclusion chromatography (SEC) method coupled with UV, multi-angle light scattering (MALS), and differential refractive index (dRI) detectors to measure the following three important AAV quality attributes (QAs): 1) total number of viral capsid particles; 2) relative capsid content (e.g., ratio of empty and full capsids); and 3) percentage of monomer or aggregates. Additionally, orthogonal methods using dynamic light scattering (DLS) and field flow fractionation (FFF) will be compared.
AAV User Meeting: Secrets to the successful quantification of AAV by light scattering
We will provide step-by-step training on how to use SEC-UV-MALS-dRI, protein conjugate analysis in ASTRA software, and additional calculations to measure AAV quality attributes (QAs). The QAs include: 1) total number of viral capsid particles; 2) relative capsid content (e.g., ratio of empty and full capsids); and 3) percentage of monomer or aggregates. We will also be available to answer any of your questions regarding DLS and FFF applications and analysis.
2019 Past User Meetings
- Indianapolis Light Scattering User Meeting held in Indianapolis, IN
- Toronto Light Scattering User Meeting held in Toronto, Ontario
- European User Meetings and Seminars held in various locations
- Boston Eclipse FFF User Meeting held in Woburn, MA
- San Diego Protein & Biotech User Meeting held in San Diego, CA
- DC Regional Light Scattering User Meeting held in Bethesda, MD
- St. Louis Light Scattering User Meeting held in in St. Louis, MO
- Cleveland User Meeting and Workshop held in Cleveland, OH
- SF Bay Area Protein & Biotech User Meeting held in San Mateo, CA
- Philadelphia Light Scattering User Meetings & Workshop held in Philadelphia, PA
- Houston Region Light Scattering User Meeting held in Houston, TX
- San Diego Region Protein & Biotech User Meeting held in San Diego, CA
- Northeast Light Scattering Short Courses & User Meetings held in Woburn, MA
2018 Past User Meetings
- Raleigh Region Light Scattering User Meeting held in Raleigh, NC
- Atlanta Region Light Scattering User Meeting held in Atlanta, GA
- Boulder, CO Light Scattering User Meeting held in Boulder, CO
- Minneapolis Light Scattering User Meeting held in Minneapolis, MN
- Toronto Light Scattering User Meeting held in Toronto, Ontario
- Southern CA Protein/Biotech User Meeting held in San Diego, CA
- Chicago Polymer/Nanoparticle Light Scattering User Meeting held in Chicago, IL
- Indianapolis Region Light Scattering User Meeting held in Indianapolis, IN
- DC Region Light Scattering User Meeting held in Bethesda, MD
- Mid-Atlantic Polymer & Nanoparticle User Meeting held in Philadeliphia, PA
- Mid-Atlantic Protein & Biotech User Meeting held in Princeton, NJ
- Northeast Protein & Biotech User Meeting held in Woburn, MA
- SF Bay Area Protein/Biotech User Meeting held in San Mateo, CA
2017 User Meetings
- DC Region Light Scattering User Meeting held in Gaithersburg, MD
- Indianapolis Region Light Scattering User Meeting held in Indianapolis, IN
- Mid-Atlantic Protein & Biotech User Meeting held in Princeton, NJ
- Research Triangle Protein & Biotech User Meeting held in Chapel Hill, NC
- Southern CA Protein/Biotech User Meeting held in San Diego, CA
Want a Protein/Biotech or Polymer/Nanoparticle User Meeting to happen in your region?
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