On-line Differential Refractometers for HPLC and UHPLC
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Optilab
An on-line differential refractometer with EXtended range for universal concentration and dn/dc measurements.
The Optilab T-rEX provides both exquisite sensitivity and 50 times the dynamic range of every other RI detector available. It is the only on-line detector offering temperature control both above and below ambient, as well as measurement of the absolute refractive index of solvents. A high concentration version measures protein concentration up to 180 mg/mL.
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Optilab UT-rEX
Universal concentration measurement for use with all UHPLC systems.
The Optilab UT-rEX is a unique Refractive Index detector that offers high sensitivity and 50 times the dynamic range of every other UHPLC RI detector. Like the Optilab T-rEX, it offers temperature control both above and below ambient, as well as measurement of the absolute refractive index of solvents.
Feature Comparison
| Capabilities | Optilab | Optilab HC | Optilab UT-rEX |
| Differential Refractive Index | |||
| Range | -0.0047 – +0.0047 RIU | -0.0026 – +0.034 RIU | -0.0047 – +0.0047 RIU |
| Peak-to-Peak Noise | ± 7.5 x 10-10 RIU | ± 1.5 x 10-9 RIU | ± 1.5 x 10-9 RIU |
| Dynamic Range | 12,000,000:1 | 23,000,000:1 | 6,000,000:1 |
| Acquisition Period | 0.1 – 5 seconds/sample | 0.1 – 5 seconds/sample | 0.04 – 5 seconds/sample |
| Absolute Refractive Index | |||
| Range | 1.2 – 1.8 RIU | 1.2 – 1.8 RIU | 1.2 – 1.8 RIU |
| Sensitivity | ± 0.002 RIU | ± 0.002 RIU | ± 0.002 RIU |
| Fluidics | |||
| Band Broadening | < 20 µL | < 20 µL | < 4 µL |
| Flow Cell & Inlet Tubing Volume | 51.4 µL | 51.4 µL | 13.9 µL |
| Sample Temperature | 4°C – 65°C | 4°C – 65°C | 4°C – 65°C |