Wyatt Technology

Upcoming Live Webinars

Characterizing Protein-Nucleic Acid Interactions by Light Scattering

Join us for a webinar on August 21 at 8:00 AM PDT | 11:00 AM EDT | 17:00 CEST

Harnessing the interactions between DNA, RNA, and proteins holds much promise for detecting biomarkers, diagnosing disease, and improving cancer-targeting therapeutics. Quantifying these interactions is essential for understanding and controlling their biomolecular mechanisms. Multi-angle light scattering (MALS) is a powerful tool for directly measuring molar masses of proteins, nucleic acids, and complexes in solution without fluorescent or radio labeling.

In this webcast, an expert will present two complementary light-scattering techniques for determining the stoichiometry and affinity of interactions between proteins and nucleic acids:

  • Size-exclusion chromatography coupled with MALS, ultraviolet, and differential refractive index detection (SEC–MALS) analyzes each of the species present in a solution of macromolecules
  • Composition-gradient MALS (CG–MALS) quantifies the binding affinity and stoichiometry of biomolecular complexes, including multi-step reactions, label-free, and immobilization-free

Application examples will focus on protein-DNA and protein-RNA complexes.

Webinar Registration

A Quick Guide to Properly Measuring Zeta Potential and Particle Size for Challenging Samples

Join us for a webinar on September 25 at 8:00 AM PDT | 11:00 AM EDT | 17:00 CEST

Dr. Jason Lin has extensive experience characterizing many types of analytes using light scattering, including some that have been quite challenging.

In this webinar he will present methods and techniques that can be used to overcome common challenges when measuring zeta potential and particle size.

The webinar will cover two main light scattering techniques: dynamic light scattering (DLS) and phase analysis light scattering (PALS). Each technique will be introduced in terms of theory and instrumentation setup. This will be followed with descriptions of common challenges that can arise and specific solutions to overcome these challenges.

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Recent Webinars

Previous webinars may be viewed in our Webinar Library. The following recent webinars are now available:


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Ultimate Guide

Thirteen key questions to ask when buying a Multi-Angle Light Scattering (MALS) or Dynamic Light Scattering (DLS) instrument.

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Solutions Catalog

Our Solutions Catalog combines Wyatt's product lines, applications and services into a single comprehensive booklet.

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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.

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