Upcoming Live Webinars
Quality attributes and extended characterization of lentiviral and gammaretroviral vectors using light scattering
Quality attributes and extended characterization of lentiviral and gammaretroviral vectors using light scattering
Join us for a webinar on April 20, 8:00 AM PDT | 11:00 AM EDT | 17:00 CEST
Lentiviral and gammaretroviral vectors are the most popular retroviral vectors used in gene and cell therapies with more than 300 clinical trials currently underway in Phase II and Phase III. Quantifying quality attributes of these retroviral vectors is of increasing importance as they enter into the late development stages. In this webinar we demonstrate the use of two analytical techniques, batch dynamic light scattering (DLS) for rapid, low-resolution measurements and multi-angle light scattering in combination with field-flow fractionation (FFF-MALS) for extended characterization of viral vectors. We will discuss methods for evaluation of the size distribution and physical titer, impurity profiling, in-depth assessment of aggregation, and lot-to-lot variability.
Recent Webinars
Previous webinars may be viewed in our Webinar Library. The following recent webinars are now available:
Characterization and formulation of therapeutic macromolecules using light scattering
Ozan Kumru, Ph.D., University of Kansas Vaccine Analytics and Formulation Center, and Dan Some, Ph.D., Wyatt Technology
March 24, 2021
Therapeutic Proteins in Biological Fluids: Size Characterization Using AF4 with Fluorescence and SPR Detection
Lars Nilsson, Ph.D., Lund University, and Christoph Johann, Ph.D., Wyatt Technology
February 24, 2021
Characterizing Polymers and Polymer Aggregates Using SEC-MALS and Batch-Mode MALS
John Matson, Ph.D., Virginia Tech
January 27, 2021
Quantify Viral Vector Attributes with Light Scattering
John Champagne, Ph.D., Wyatt Technology
January 19, 2021
Virtual User Meeting – Screening for stability: Characterizing formulations with DLS
Wyatt Technology
December 8 & 10, 2020
Measuring physical properties of liposomes and LNPs for RNA delivery with multidetector asymmetric-flow field-flow fractionation
Fanny Caputo, Ph.D., SINTEF, and Christoph Johann, Ph.D., Wyatt Technology
December 15, 2020
Rational use of dynamic light scattering for the characterization of cytokines, bispecific antibody fusion proteins and binary antibody mixtures
Hristo Svilenov, Ph.D., Technical University of Munich, and Sophia Kenrick, Ph.D., Wyatt Technology
November 17, 2020
A breakthrough development in FFF-MALS – raising performance and usability to a new level
Christoph Johann, Ph.D., and Chris Deng, Ph.D., Wyatt Technology
October 27, 2020Virtual User Meeting – New Methods and Applications in Field Flow Fractionation
Wyatt Technology
October 22, 2020
Real-Time Process Analytics and Control for Vaccine Nanoparticles and Macromolecules
Daniel Some, Ph.D., Wyatt Technology
September 22, 2020
Follow us on 
or join one of our groups Social@Wyatt
Understanding Polymer Properties with Multi-Angle Light Scattering
Join us for a webinar on May 12, 8:00 AM PDT | 11:00 AM EDT | 17:00 CEST
Polymers, both of synthetic and natural origin, are an integral part of our everyday life. In contrast to low-molar-mass organic compounds, polymer samples of identical chemical composition can differ substantially by their application properties. Many important polymer properties are affected by the molar mass distribution and structural topology of the polymer chains. A multi-angle light scattering (MALS) detector following an analytical separation technique such as SEC or FFF, often in combination with an online viscometer, can provide detailed information about the molecular structure and thus proper understanding of the properties and behavior of a very wide range of polymers.
