Upcoming Live Webinars
Advances in automated dynamic light scattering characterization and zeta potential of macromolecules and nanoparticles using the DynaPro™ ZetaStar™
Join us for a webinar on Tuesday, October 10 at 8:00 AM PDT | 11:00 AM EDT | 17:00 CEST
Size, polydispersity, and charge or zeta potential are important attributes of a particle or macromolecule because they uniquely describe the ID, state, and stability of a sample. Equally important to measuring these properties is conducting the measurement in high salt solutions, that mimic physiological conditions. Unfortunately, these measurements tend to be cumbersome and time-consuming. However, this doesn’t need to be the case, in this webinar, we will introduce the capability for increasing efficiency through automated, unattended screening of a large range of sample and buffer conditions. This is especially relevant for scientists working to develop and optimize formulations of lipid nanoparticles, metal nanoparticles and complex proteins.
Shining Light on AAVs: Using Light Scattering Technologies to Solve Challenges in Characterization
Join us for a webinar on Wednesday, October 18 at 8:00 AM PDT | 11:00 AM EDT | 17:00 CEST
With the rising clinical and commercial successes of AAV-based gene therapies, there is an ever-growing demand for robust, platform analytical technologies that can help ensure better product quality, safety, and efficacy. Size exclusion chromatography (SEC) and Field Flow Fractionation (FFF), coupled with multi-angle light scattering technologies (MALS), are rapidly emerging as transformative technologies for rapid and accurate characterization of AAV samples. Critical Quality Attributes (CQAs) such as capsid titer, genome titer, empty/full, % aggregation and purity of various AAV serotypes can all be obtained in a single measurement. This multi-attribute approach dramatically reduces operational costs and reduces drug development timelines.
Determination of critical product parameters for proteins from research to production
Join us for a webinar on Wednesday, November 8 at 8:00 AM PST | 11:00 AM EST | 17:00 CET
During this webinar the diversity of various light scattering techniques for characterizing a wide range of protein samples and their applicability in pharmaceutical research will be shared.
We will start by highlighting the potential of dynamic light scattering (DLS) as a tool for rapid and straightforward aggregate detection, as well as its value in executing extensive formulation studies and predicting stability.
This will be followed by applications of multi-angle light scattering (SEC-MALS and FFF-MALS), showcasing its ability to provide absolute molecular weight, oligomerization, and conjugate analyses.
We will conclude with an introduction to real-time MALS, offering real-time insights and enabling direct process influence on attributes such as molar mass, size, and particle concentration.
Previous webinars may be viewed in our Webinar Library. The following recent webinars are now available:
Susanne Boye, Ph.D., Institut Makromolekulare Chemie and Robert Mildner, Ph.D., Waters | Wyatt Technology
August 29, 2023
Request: Multi-Detector Asymmetric-Flow Field-Flow Fractionation for Nanoparticle Analysis in Complex Matrices
Stacey Louie, Ph.D., University of Houston and Nemal Gobalasingham, Ph.D., Waters | Wyatt Technology
July 25, 2023
Leo Liu, Ph.D., Waters | Wyatt Technology
July 11, 2023
Request: Well-behaved or troublemaker? How high-throughput Dynamic Light Scattering (DLS) boosts developability & stability of biotherapeutics
Felix Gloge, Ph.D., and Christian Sieg, Ph.D., Waters | Wyatt Technology
June 13, 2023
Request: Characterizing Critical Quality Attributes of Outer Membrane Vesicles for Conjugate Vaccines
Robert van der Put, Ph.D., Intravacc, and Roger Scherrer, Ph.D., Wyatt Technology
May 23, 2023
Jonathan Kingsbury, Ph.D., Sanofi and Xujun Zhang, Ph.D., Wyatt Technology
April 11, 2023
Clara Pérez Peinado, Ph.D., Janssen and Dan Some, Ph.D., Wyatt Technology
March 7, 2023
Michelle Chen, Ph.D., Wyatt Technology
January 18, 2023
Request: Polymer Characterization Using Field-Flow Fractionation Combined with Multi-Angle Light Scattering
Frederic Villeau, Ph.D., Ecole d'Ingenieurs de Purpan, Marie Hennetier, Ph.D., Ecole d'Ingenieurs de Purpan and Lionel Rouzic, Ph.D., Wyatt Technology
December 8, 2022
Request: Optimizing microfluidic LNP formulations with in-line particle size and concentration measurements
Jeremie Parot, Ph.D., SINTEF and Daniel Some, Ph.D., Wyatt Technology
November 17, 2022
Request: Exploring protein oligomerization and stoichiometry with SEC-MALS: Case studies from phage-bacteria conflict
Kevin Corbett, Ph.D., University of California, San Diego and Nayanthara Dharmaratne, Ph.D., Wyatt Technology
October 18, 2022
Request: Advantages of FFF-MALS over SEC-MALS for the Determination of Molar Mass and Size Distribution of Polysaccharides
Sandesh Neupane, Ph.D., Wyatt Technology
September 27, 2022
Dan Some, Ph.D., Wyatt Technology
August 23, 2022
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