Upcoming Live Webinars

FFF 2.0: Obtaining high resolution distributions of nanoparticle size and zeta potential, with less time, less effort and more confidence

Join us for a webinar on July 24 at 8:00 AM PDT | 11:00 AM EDT | 17:00 CEST

This webinar will show how complex nanosuspensions, consisting of macromolecules and nanoparticles with sizes 1-1000 nm, can be characterized with high resolution using field-flow fractionation (FFF) coupled to a multi-angle light scattering (MALS) detector. In the life sciences and medicinal fields, FFF-MALS is beneficial for characterizing and isolating gene vectors, liposomal drug formulations, protein aggregates and exosomal biomarkers, but it is also useful in environmental and industrial applications such as lignocellulose, starch, latex paints and effluent or soil particulates.

The principle of separation by Flow-FFF and determination of size using MALS is presented. The FFF 2.0 workflow and novel software platform are demonstrated, from initial simulations and rationalized method refinement to the final, fully-optimized method with data analysis. In addition, the new method of determining electrophoretic mobility by Electrical/Asymmetric Flow-FFF (EAF4) is introduced, with examples to include particles and proteins.

Recent Webinars

Previous webinars may be viewed in our Webinar Library. The following recent webinars are now available:

• Crystallized Biotherapeutics: Optimizing mAb Crystallization using Light Scattering
• Separation and Characterization of Complex (Bio)macromolecular Architectures
• Understanding monoclonal antibody unfolding and aggregation
• Applications of Light Scattering to HIV Integrase Structural Biology and Drug Discovery
• µSEC-MALS adds Multi-Angle Light Scattering to UHP-SEC for Measurement of Absolute Molecular Weight and Size
• Applications of Analytical Light Scattering in a Biophysics Core Facility
• Quickly Screen Peptides, Proteins and Nanoparticles for Size and Aggregation Using Advanced Methods
• Advances in High-Throughput Screening of Aggregation, Stability and Viscosity Utilizing Light Scattering in Microwell Plates
• Absolute Characterization of Polymeric Excipients with Size Exclusion Chromatography and Light Scattering
• Absolute Characterization of Glycoproteins and their Interactions with Proteins and Antibodies by Light Scattering
• Essential Polymer Characterization with MALS and FFF
• Small, but bright: µSEC-MALS adds light scattering to UHP-SEC for biophysical characterization of biotherapeutics
• Characterizing Molecular Structure in Synthetic and Natural Polymers by Multi-Angle Light Scattering
• Innovations and Applications of UHP-SEC and Multi-Angle Light Scattering (MALS) for the Analysis of Biotherapeutic Proteins
• Advances in online viscometry: extending the limits of detection for intrinsic viscosity and hydrodynamic radius

Follow us on or join one of our groups Social@Wyatt