Request: Towards Well-Characterized Proteins and Protein Conjugates Using SEC-MALS

Michelle Chen

Key Learning Objectives:

  • Explore the different light scattering (LS) techniques and their capabilities in measuring protein properties.
  • Delve into the applications of SEC-MALS technique across various stages of protein development, including early discovery, process development, and quality assurance and quality control (QA/QC).
  • Uncover the analytical power of SEC-MALS in characterizing different protein conjugates, such as antibody-drug conjugates (ADCs), antibody-oligo conjugates (AOCs), ribonucleoproteins (RNPs), adeno-associated viruses (AAVs), and lipid nanoparticles (LNPs).