Wyatt Technology

Characterizing Protein Conjugates and Their Aggregates by Light Scattering


Presented Live: June 10, 2009

Topics Covered

  • The latest advancements in MALS and their applications for measuring protein oligomeric states and aggregation, as well as characterizing protein conjugates (such as pegylated proteins or membrane proteins)
  • The combination of MALS and FFF for separating and characterizing various protein solutions, viruses, virus-like particles, and liposomes




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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.

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