Wyatt Technology

Optimizing Protein Biotherapeutic Formulations with the Light Scattering Toolkit

 

Presented Live: April 20, 2016

Speaker: Daniel Some, Ph.D. Principal Scientist and Director of Marketing at Wyatt

Abstract: Biophysical techniques based on static and dynamic light scattering address many of the key analytical challenges in biotherapeutic formulation development, including screening for aggregation, colloidal and conformational stability, viscosity and chemical modifications. This seminar will review light scattering technology and instrumentation, then present select examples illustrating how complete light scattering solutions facilitate rapid and effective development of protein-based biotherapeutic formulations.

 

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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.



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