Another path to polymer characterization
When coupled with a concentration detector such as the Optilab T-rEX, the ViscoStar II can be used to derive the intrinsic viscosity of polymers. The intrinsic viscosity, in turn, can be used to derive the hydrodynamic radius and shape information about a macromolecule in solution.
Universal calibration is a parallel technique to SEC-MALS for determining molecular weight, commonly used to characterize polymers. While universal calibration overcomes some of the problematic issues associated with column calibration by reference standards, it does not account for non-ideal column behavior caused by chemical solute-column interactions or hyperbranching. Still, if samples are known to be well-behaved, universal calibration can be a useful check with or without MALS data.
High sensitivity, equivalent to 1 µg/mL of 30 kDa polystyrene at 0.5 mL/min or ~ 0.35 µg injected onto a standard GPC column
Measurement range corresponds to over 14 mg/mL of 30 kDa polystyrene
Temperature control from 4°C - 60°C for polymers that require a range of temperatures
High-resolution, touch-screen front panel displays data graphs and diagnostics, even with the host computer turned off
Most viscometers only have an internal heater, and as a result, can only regulate temperatures 10°C above room temperature. The ViscoStar II is the only viscometer that can regulate temperatures at or below room temperature, as well as above - between 4°C and 60°C.
With the ViscoStar II and the band broadening correction in ASTRA, you can correct for interdetector broadening and can display the true, constant intrinsic viscosity.