AN1007: Characterization of Polymer Degradation with SEC-MALS

Multi-angle light scattering coupled with size-exclusion chromatography (SEC-MALS) is a powerful technique for polymer characterization, offering detailed insights into molar mass, size, and distributions without the need for calibration standards.

This application note highlights the capabilities of SEC-MALS in analyzing polymer degradation using polydioxanone (PDO) surgical sutures as a case study. It explores the various practical metrics used for analysis, showcasing the effectiveness of SEC-MALS in providing comprehensive data on polymer degradation.