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  • AN1617: AAV CQA Analysis by SEC-MALS

AN1617: AAV critical quality attribute analysis by SEC-MALS

Biophysical characterization with SEC-MALS determines multiple CQAs of adeno-associated viruses bearing RNA or DNA payloads for gene therapy, including concentration, degree of aggregation and ratio of empty to full capsids.

   

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Thirteen key questions to ask when buying a Multi-Angle Light Scattering (MALS) or Dynamic Light Scattering (DLS) instrument.

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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.



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