On-Line MALS-DLS Characterization of Proteins with Unusual Elution Properties

MALS-DLS Characterization

On-line quasi-elastic light scattering (QELS) together with MALS detection provides insight into the structure of polymers when both hydrodynamic and root-mean square radii are measured. In this application note, we report how the on-line WyattQELS detector helps to evaluate the quality of the SEC separation and estimate the shape of proteins.