From Proteins to AAVs and LNPs: Multi-Attribute Quantification (MAQ) by Light Scattering request

Michelle Chen

Key Learning Objectives:

  • Introduction to DLS and MALS, and what they can measure
  • How DLS screens size, polydispersity, particle concentration and stability of AAV- or LNP-based gene therapy products
  • How SEC-MALS and FFF-MALS provide multi-attribute quantitation (MAQ) of gene vectors
  • Understanding the quality attributes quantified by MALS, DLS and related techniques