DLS Application Notes

Cuvette and microwell-plate based sizing with the DynaPro^® Plate Reader III and DynaPro^® NanoStar^®.

Biotherapeutics
Proteins
Biopolymers
Synthetic Polymers
Nanoparticles
Other
General

White Papers

WP9003: VLP Characterization with the Light Scattering Toolbox
Aggregate Analyses by Light Scattering – Complementary and Orthogonal [poster]
PL9008: Key publications on the characterization of gene vectors by light scattering
PL5011: Key publications on high-throughput screening of therapeutic protein formulations by light scattering
WP5010: High-Throughput DLS for Biotherapeutics Development
WP5009: Protein Quality Control in SPR and BLI High-Throughput Screening Studies
WP5003: DynaPro® Plate Reader III Automated dynamic and static light scattering in microwell plates for fast, productive development of biologics
WP5004: The Diffusion Interaction Parameter kD as an Indicator of Colloidal and Thermal Stability
E-book: Advancing biopharma analysis with light scattering
Characterizing Stable Protein Formulations

Application Notes

White Papers

Application Notes

White Papers

Application Notes

White Papers

E-book: Beyond GPC Light Scattering for Absolute Polymer Characterization

Application Notes

Polymersomes (Vesicles)

White Papers

Application Notes

White Papers

WP: DYNAMICS SP: Security Pack for 21 CFR Part 11 compliance

DLS Application Notes

White Papers

WP9003: VLP Characterization with the Light Scattering Toolbox

Aggregate Analyses by Light Scattering – Complementary and Orthogonal [poster]

PL9008: Key publications on the characterization of gene vectors by light scattering

PL5011: Key publications on high-throughput screening of therapeutic protein formulations by light scattering

WP5010: High-Throughput DLS for Biotherapeutics Development

WP5009: Protein Quality Control in SPR and BLI High-Throughput Screening Studies

WP5003: DynaPro® Plate Reader III Automated dynamic and static light scattering in microwell plates for fast, productive development of biologics

WP5004: The Diffusion Interaction Parameter kD as an Indicator of Colloidal and Thermal Stability

E-book: Advancing biopharma analysis with light scattering

Characterizing Stable Protein Formulations

Application Notes

AN4004: Conformation of a Trimeric Protein by DLS

AN4006: Studying the performance of surfactants as chaotropic agents in protein formulation by DLS

AN5008: High-throughput freeze-thaw stability studies with the DynaPro Plate Reader

AN9010: Characterizing lentiviral and gammaretroviral vectors by batch DLS and FFF-MALS

AN4003: Influence of heating rates on the thermostability characterization of antibodies by DLS and SLS

AN5007: AAV quantitation and stability analysis by batch DLS

AN5001: High-Throughput Screening of TiO2 Nanoparticle Dispersions in Cell Culture Media

AN5005: Characterization and Formulation Screening of mAb and Antibody-Drug Conjugates (ADCs) by High-throughput DLS

Next Steps in AAV Characterization via Light Scattering Measuring AAV Critical Quality Attributes [poster]

Verification of Protein Aggregate Removal

Vaccines: Time-Resolved Structural Changes and Aggregation in Influenza Virus [poster]

Vaccines: Forced Aggregation of Antigens [poster]

Screening High-Concentration Protein-Protein Interactions

pH Dependent Monomer-Dimer Equilibrium Constants for Glycinamide ribonucleotide transformylase (GART)

Aggregation of Antibody-Drug Conjugates [poster]

Aggregation of a Recombinant Protein: Comparison of SEC-MALS, SEC-QELS and Plate-Based DLS [poster]

White Papers

WP9003: VLP Characterization with the Light Scattering Toolbox

Aggregate Analyses by Light Scattering – Complementary and Orthogonal [poster]

WP5009: Protein Quality Control in SPR and BLI High-Throughput Screening Studies

WP5003: DynaPro® Plate Reader III Automated dynamic and static light scattering in microwell plates for fast, productive development of biologics

Application Notes

PH6001: Charge-Mediated Colloidal Stability of mAbs Formulation

AN4007: Particle Size Analysis by DLS for Optimisation of Protein Complexes for Measurement by Small-Angle Neutron Scattering

AN4004: Conformation of a Trimeric Protein by DLS

AN4006: Studying the performance of surfactants as chaotropic agents in protein formulation by DLS

AN5008: High-throughput freeze-thaw stability studies with the DynaPro Plate Reader

AN4003: Influence of heating rates on the thermostability characterization of antibodies by DLS and SLS

Next Steps in AAV Characterization via Light Scattering Measuring AAV Critical Quality Attributes [poster]

AN4002: pH effects on stability and homogeneity of a protein complex analyzed by DLS

AN4001: Organic-phase encapsulation in protein-based nanocapsules studied by DLS

Protein Folding

pH Effects on Stability and Homogeneity of Protein Complex

pH Dependent Monomer-Dimer Equilibrium Constants for Glycinamide ribonucleotide transformylase (GART)

Monitoring RNA Folding Intermediates [poster]

Monitoring Protein Complex Formation in Solution

Glycolytic Enzyme Enolase

DNA and RNA Repair Enzymes

Dental Enamels

Conjugate Analysis: Lipid Transport Proteins [poster]

Characterization of α-synuclein Oligomerization

AN7301: Molar Mass and Size of Globular and Glycoproteins by SEC-MALS-QELS

AN5006: Probing the aggregation rate of a Tau protein with DLS and SLS

Aggregation of Combinatorial Tau Protein [poster]

White Papers

WP9002: Characterization of Fluorescent Macromolecules and Nanoparticles

E-book: Beyond GPC Light Scattering for Absolute Polymer Characterization

Application Notes

Elastin-Like Polypeptides (ELP) Block Co-Polymers

AN1303: Chondroitin Sulfate MW and Size by SEC-MALS-QELS

White Papers

E-book: Beyond GPC Light Scattering for Absolute Polymer Characterization

Application Notes

Polymersomes (Vesicles)

White Papers

WP9002: Characterization of Fluorescent Macromolecules and Nanoparticles

WP9001: Nanoparticle Characterization with the Light Scattering Toolkit

Application Notes

AN4008: Rapid Extracellular Vesicles Purification and Analysis

AN9010: Characterizing lentiviral and gammaretroviral vectors by batch DLS and FFF-MALS

AN5001: High-Throughput Screening of TiO2 Nanoparticle Dispersions in Cell Culture Media

AN4001: Organic-phase encapsulation in protein-based nanocapsules studied by DLS

Vesicle Size Distribution Analysis

Real-Time Monitoring of Macromolecular Complex Assembly and Disassembly

Quantum Dot Sizing by DLS

Polymersomes (Vesicles)

Nanoparticles (NPs) and Biology