Protein-Protein-Small Molecule Interactions – Inhibition Kinetics and Dissociation

Calypso-DAWN-Optilab Setup

Quantification of the kinetic rates of protein association, dissociation, and aggregation is an essential factor in understanding and ultimately manipulating these phenomena. Multi-angle, static light scattering (MALS) is a widespread technology for characterizing macromolecules in solution, providing an absolute measure of molar mass and size.