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WP2608: Lipid Nanoparticle and Liposome Characterization with FFF-MALS-DLS

Liposomes and Lipid nanoparticles serve as versatile drug delivery systems, offering control over composition, structure, and morphology, where these properties can be tailored to each specific pharmaceutical application. Comprehensive characterization of the particles by FFF-MALS-DLS is essential for rapid and effective pharmaceutical product development as well as for regulatory approval.


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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.

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