Request: Advancing GLP-1 Analog Drug Development Using a Variety of Light Scattering Techniques
Peptides like GLP-1a tend to self-associate—sometimes forming reversible oligomers, sometimes forming irreversible aggregates.
Discover how size-exclusion chromatography coupled with multi-angle light scattering (SEC-MALS) under native and denaturing conditions enables precise characterization of GLP-1a products.
Key topics:
- Fundamentals of light scattering
- Molar mass and size of GLP-1a oligomers
- Case studies involving semaglutide and liraglutide
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