High-throughput Analytics for Formulation and Process Development of Bio- and Nano-therapeutics

Dan Some

Presented by: Daniel Some, Ph.D., Principal Scientist, Wyatt Technology
Presented Live: April 12, 2017

Timely, effective development of therapeutic proteins and nanoparticles requires comprehensive analytics across a variety of conditions, excipients, and candidate molecules.

A versatile and powerful method for obtaining these analytics is high-throughput dynamic light scattering (HT-DLS), performed in low-volume microwell plates. While DLS is widely used to characterize size and aggregation of particles from nanometers to microns, HT-DLS extends those measurements to cover a diverse array of screening techniques designed to weed out low-performing formulations prior to costly stability studies.

This webinar covers the use of HT-DLS in evaluating size, aggregation, colloidal stability, and conformational stability of proteins and nanoparticles in the context of screening formulation and process development conditions.

Q&A Webinar Q & A