Presented by: Daniel Some, Ph.D., Wyatt Technology
Presented Live: July 23, 2020
Reliable biophysical characterization is a central challenge in the development of gene therapies. Robust analytical tools based on light scattering, that have been essential in the development and commercialization of monoclonal antibodies and virus-based vaccines, are also suitable for gene vectors, whether viral or non-viral. This talk will highlight the applications of multi-angle and dynamic light scattering for the determination of critical quality attributes of gene vectors. Topics to be covered include analysis of AAVs, lentiviral vectors and synthetic vectors as well as PAT applications for monitoring particle size in production.