Quantifying Affinity and Stoichiometry of Biomolecular Interactions by Composition-Gradient Multi-Angle Light Scattering (CG-MALS)
Presented Live: April 23, 2013
Composition-Gradient, Multi-Angle Light Scattering (CG-MALS) is a powerful, label-free technique for quantifying the affinity and stoichiometry of macromolecular interactions. CG-MALS measures interactions entirely in solution without tagging or immobilization, which can confound measurements by other techniques. In this webinar, we will demonstrate how CG-MALS has been successfully applied to the study of self-association, hetero-association with simple stoichiometry, and complex combinations of self- and hetero-association.