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Separation and Characterization of Macromolecular and Supramolecular Structures by Light Scattering Webinar


Presented Live: February 26, 2019

Speakers: Ema Žagar, Ph.D.

Comprehensive characterization of complex macromolecular structures is challenging since no single analytical technique provides adequate information regarding all the different distributions. Hyphenated techniques, that couple separation by asymmetric-flow field-flow fractionation (AF4) or size-exclusion chromatography (SEC) with a multi-detection system, do provide detailed insight into such structures. A versatile online multi-detection system includes multi-angle light-scattering (MALS), dynamic light scattering (DLS), ultraviolet (UV) and refractive-index (RI) detectors.


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Wyatt Technology is the recognized leader in light scattering instrumentation and software for determining the absolute molar mass, size, charge and interactions of macromolecules and nanoparticles in solution.

Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS), and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (MP-PALS), differential refractometry, and differential viscosity.

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