Methodologies for analyzing protein aggregation
Protein aggregation can occur at any stage of the development of protein-based therapeutic compounds. Michelle Chen, Director of Analytical Services at Wyatt Technology, elaborates on light scattering methodologies that have been developed for its characterization, enabling the determination of protein aggregate composition in therapeutic formulations through the application of orthogonal approaches.
Chen, M. SP2 Inter-Active November/December 2013. Link to Article