E-Book: Biopharmaceutical characterization: Improve predictive screening

Biopharmaceuticals, comprising monoclonal antibodies, antibody-drug conjugates, recombinant or fusion proteins, and bispecifics, among others, have recently gained commercial success and are rapidly changing the therapeutic landscape.

Due to their large size and complex structures, characterizing these biotherapeutics requires robust and demanding analytical techniques. Often, traditional methods used to characterize proteins fail to deliver on either the sensitivity required or the speed desired to accelerate the drug development pipeline.

Providing a versatile and reliable approach to biotherapeutic characterization, light scattering techniques are now becoming widely utilized to characterize macromolecules in solution. Contrary to most characterization methods, light scattering methods don’t rely on external calibration standards – they provide absolute measurements.

View Scientist Choice Award Winner acceptance speech by Geof Wyatt and Cliff Wyatt