Multi-Angle News – January 2018

Screening and characterizing colloidal interactions for optimal biotherapeutic formulations

Colloidal interactions arising from surface-exposed moieties on therapeutic proteins, monoclonal antibodies, antibody-drug candidates and other biopharmaceuticals lie at the heart of drug product stability.

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"Wyatt Technology is invested in the success of its customers. No instrument manufacturer does a better job of educating and supporting their users."

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Upcoming Webinar - January 23

"µSEC-MALS adds Multi-Angle Light Scattering to UHP-SEC for Measurement of Absolute Molecular Weight and Size"

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Application Note: 
The Diffusion Interaction Parameter (kD) as an Indicator of Colloidal and Thermal Stability

What can we learn about protein-protein interactions, formulation and stability from automated dynamic light scattering? Apparently, far more than is generally appreciated. This application note goes beyond aggregation, colloidal stability (kD) and thermal stability (Tonset), to examine the utility of kD(T) in elucidating the interactions that occur in monoclonal antibodies as they go through a thermal transition.

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Webinars

µSEC-MALS adds Multi-Angle Light Scattering to UHP-SEC for Measurement of Absolute Molecular Weight and Size

January 23

Presented by Vincent Hsieh, Ph.D.
Principal R&D Scientist
Wyatt Technology

Biophysical studies of HIV integrase: structural biology, drug discovery and mechanisms of action

February 27

Presented by Kushol Gupta, Ph.D.
Research Assistant Professor
Department of Biochemistry and Biophysics
Perelman School of Medicine
The University of Pennsylvania

User Meeting

SF Bay Area - February 23