AN1606: Assessing Ligand-Binding Assay Reagent Proteins

Reagent Proteins

Ligand Binding Assays (LBAs) used for large molecule drug development can necessitate conjugation of a drug to one or more different tags. To help ensure that LBAs utilizing conjugated drug reagents perform consistently over time and provide high quality data, each lot of conjugated material should be characterized functionally and biophysically prior to being incorporated into the LBA.