Wyatt Blog

We welcome blog post submissions from all Wyatt users and staff. To submit a blog, please send your article in a Word document to marketing@wyatt.com along with any photos or images in separate files.
March 13, 2018

Northeast Regional Office

March 13, 2018 - The Northeast US office was established in 2003 to give Wyatt Technology a much-needed physical presence on the east coast and has since grown into an integral part of our growing business. The location offers convenient access for regional customers to receive sales and service support, demos, LSU short courses and technical applications support. The office has a fully equipped analytical lab showcasing Wyatt’s complete lineup of instruments and also includes a number of complementary third party tools.
March 12, 2018

Are all exosomes essentially alike?

March 12, 2018 - Are all exosomes essentially alike? While proteomic, lipidomic and genomic content, as well as specific function, certainly vary with cell line and environment, common wisdom has held that the vast majority of bionanoparticles produced by cells generally have the same structure and pathway of generation. A tool for differentiating exosomes was needed in order to address this question.
December 18, 2017

Thomas Fire Update

December 18, 2017 - Dear Customers: Thank you for reaching out and keeping us in your thoughts while our region deals with the challenges associated with the Thomas Fire. While this wildfire continues to burn through portions of southern California, we thankfully report Wyatt Technology has not been adversely impacted. The air has been smoky but otherwise it’s business as usual. Unfortunately, not everyone in our region was as fortunate and so there’s a way you can help. A “Thomas Fire Fund” has been established by the United Way, American Red Cross and the California Office of Emergency Services to help those in need. Donations can be made through the United Way website at www.unitedwaythomasfirefund.org
December 15, 2017

Polymer characterization: viscosity is intrinsic

December 15, 2017 - The centrality of multi-angle light scattering to polymer characterization is widely appreciated. SEC-MALS with a DAWN® is the gold standard for determining reliable, accurate distributions of absolute molar mass and rms radius, without having to rely on column calibration, reference molecules that don’t elute like your samples, and assumptions about ideal conformation and column interactions. But once you have mastered SEC-MALS, what’s the next stage? How to obtain even deeper understanding of your macromolecules? And what are your options if SEC-MALS does not work for some of your samples?
November 14, 2017

Developing a Library of Proteins for Drug Research

November 14, 2017 - The abundance of protein drugs on the market shows there is an increasing demand for knowledge within the formulation of biologics, as Professor Pernille Harris, Principal Investigator and Coordinator of the Protein-excipient Interactions and Protein-Protein Interactions in formulation (PIPPI) project explains
October 13, 2017

Gold Seal of Quality Awarded for DAWN

October 13, 2017 - Once again our remarkable customers, along with SelectScience®, have chosen to recognize the DAWN® as an icon of instrument quality and customer delight. This month the DAWN was awarded the SelectScience Gold Seal of Quality, just the second analytical instrument in a field of thousands to receive this status.
October 4, 2017

Wyatt Customer to Win Nobel Prize in Chemistry

October 4, 2017 - Wyatt Technology congratulates its customer, Dr. Joachim Frank of Columbia University on sharing the Nobel Prize in Chemistry today with Jacques Dubochet and Richard Henderson. We are delighted to see their work developing cryo-electron microscopy recognized for its use in high-resolution structure determination of biomolecules in solution.
September 11, 2017

Virtual Method Optimization and Size Analysis for FFF

September 11, 2017 - Flow-field flow fractionation (flow-FFF) offers highly versatile separations for the analysis of complex fluids, covering a size range of macromolecules and particles from 1 nm to 10,000 nm. However, flow-FFF is often perceived as a difficult technique to learn because of the multiple parameters available for adjustment.

Our new SCOUT DPS® software simulates flow-FFF from basic physical principles, enabling the virtual optimization of flow-FFF methods and opening up the power of flow-FFF separations to non-experts. SCOUT DPS also analyzes particle size distributions (hydrodynamic radius) by elution time to increase characterization capabilities. This publication in The Column explains how it works.

August 31, 2017

UHP-SEC-MALS Analysis of NIST mAb Reference Material

August 31, 2017 - The µDAWN® multi-angle light scattering (MALS) detector was developed to meet the need for a low-volume, low-dispersion MALS instrument compatible with size-exclusion UHPLC (SE-UHPLC). Congratulations to Drs. Vincent Hsieh and Philip J. Wyatt on the publication of their article, “Measuring proteins with greater speed and resolution while reducing sample size” in Scientific Reports. The paper describes the analysis of NIST standard reference material SRM 8671, a monoclonal antibody developed to benchmark analytical instruments for the biopharmaceutical industry, with the µDAWN.
August 11, 2017

Three Wyatt Generations

August 11, 2017 - 3G isn’t just a telecommunications term anymore. It’s also an abbreviation for the three generations of Wyatts working at Wyatt Technology this summer. While there have been 2G—or two generations—of Wyatts working at Wyatt Technology for more than thirty years, this summer we welcomed Spenser Wyatt, Geof’s son, to intern under Ross Bryant, Wyatt Technology’s Vice President for Sales & Marketing, doing Market Research. Besides investigating instrument population density throughout the United States, and researching new sales tools, Spenser has audited Light Scattering University and surveyed students about their experiences at LSU.