Wyatt Blog

We welcome blog post submissions from all Wyatt users and staff. To submit a blog, please send your article in a Word document to marketing@wyatt.com along with any photos or images in separate files.
October 13, 2017

Featured Customer: Jon Pokorski, Ph.D.

October 13, 2017 - Nanoparticle sizing, protein buffer optimization for crystallization, biotherapeutic stability evaluation, critical aggregation or micelle concentration. These are some of the more common applications and uses of the DynaPro® Plate Reader, including the just-launched Plate Reader III. But, some of our Plate Reader customers are far more creative than the average scientist.
October 13, 2017

Gold Seal of Quality Awarded for DAWN

October 13, 2017 - Once again our remarkable customers, along with SelectScience®, have chosen to recognize the DAWN® as an icon of instrument quality and customer delight. This month the DAWN was awarded the SelectScience Gold Seal of Quality, just the second analytical instrument in a field of thousands to receive this status.
October 4, 2017

Wyatt Customer to Win Nobel Prize in Chemistry

October 4, 2017 - Wyatt Technology congratulates its customer, Dr. Joachim Frank of Columbia University on sharing the Nobel Prize in Chemistry today with Jacques Dubochet and Richard Henderson. We are delighted to see their work developing cryo-electron microscopy recognized for its use in high-resolution structure determination of biomolecules in solution.
September 19, 2017

Featured Customer: Professor Stuart Rowan

September 19, 2017 - We are pleased to announce that Prof. Stuart Rowan is our Featured Customer for September 2017. As Professor of Molecular Engineering at the University of Chicago’s Institute for Molecular Engineering, Dr. Rowan’s research focuses on the construction and properties of structurally-dynamic polymeric materials such as self-healing materials. He and his group study metallosupramolecular and stimuli-responsive polymers, cellulose nanocrystals in biomimetic and porous systems, and reversible covalent chemistry.
September 11, 2017

Virtual Method Optimization and Size Analysis for FFF

September 11, 2017 - Flow-field flow fractionation (flow-FFF) offers highly versatile separations for the analysis of complex fluids, covering a size range of macromolecules and particles from 1 nm to 10,000 nm. However, flow-FFF is often perceived as a difficult technique to learn because of the multiple parameters available for adjustment.

Our new SCOUT DPS® software simulates flow-FFF from basic physical principles, enabling the virtual optimization of flow-FFF methods and opening up the power of flow-FFF separations to non-experts. SCOUT DPS also analyzes particle size distributions (hydrodynamic radius) by elution time to increase characterization capabilities. This publication in The Column explains how it works.

August 31, 2017

UHP-SEC-MALS Analysis of NIST mAb Reference Material

August 31, 2017 - The µDAWN® multi-angle light scattering (MALS) detector was developed to meet the need for a low-volume, low-dispersion MALS instrument compatible with size-exclusion UHPLC (SE-UHPLC). Congratulations to Drs. Vincent Hsieh and Philip J. Wyatt on the publication of their article, “Measuring proteins with greater speed and resolution while reducing sample size” in Scientific Reports. The paper describes the analysis of NIST standard reference material SRM 8671, a monoclonal antibody developed to benchmark analytical instruments for the biopharmaceutical industry, with the µDAWN.
August 11, 2017

Three Wyatt Generations

August 11, 2017 - 3G isn’t just a telecommunications term anymore. It’s also an abbreviation for the three generations of Wyatts working at Wyatt Technology this summer. While there have been 2G—or two generations—of Wyatts working at Wyatt Technology for more than thirty years, this summer we welcomed Spenser Wyatt, Geof’s son, to intern under Ross Bryant, Wyatt Technology’s Vice President for Sales & Marketing, doing Market Research. Besides investigating instrument population density throughout the United States, and researching new sales tools, Spenser has audited Light Scattering University and surveyed students about their experiences at LSU.
August 10, 2017

Featured Customer – Professor Christopher Ellison

August 10, 2017 - It was our pleasure to host Prof. Christopher Ellison at the June LSU (Light Scattering University) course–held, as always, at Wyatt’s headquarters in beautiful Santa Barbara, California. As Piercy Professor of Chemical Engineering and Materials Science at the University of Minnesota, Dr. Ellison’s research pushes the boundaries of molecular architecture: he and his group create and investigate nanostructured polymeric systems for a wide array of advanced applications including photolithography, microelectronic device design, battery design, and general nano-scale manufacturing.
July 1, 2017

Drug discovery: Finding, Then Losing, Then Finding Again Colloidal Aggregates of Small-molecule Drugs with DLS

July 1, 2017 - Dynamic light scattering is not just for proteins and nanoparticles. In the field of small-molecule drug discovery, high-throughput DLS with the DynaPro Plate Reader II has at least one key role - preventing the accumulation of misleading hits, or false positives, that are a result of aggregated compounds. Brian Shoichet's UCSF lab has been instrumental in elucidating the mechanism of action and prevention of these promiscuous inhibitors, utilizing the DynaPro PRII for detection and formulation. Read highlights of his publications and a link to a recent online interview.
June 17, 2017

Silver Seal of Quality Awarded for DAWN

June 17, 2017 - We are pleased to announce to extension of SelectScience's Seal of Quality to the DAWN, following its recognition as Reviewers' Choice Instrument of the Year for 2017. More on the inside story here.