This work presents a new application of osmotic coefficients from CG-MALS measurements. Read our application note to learn more.
This eBook explains how light scattering, across its various flavors, is used to characterize vaccines.
Learn how to characterize polymers in organic solvents by FFF-MALS by reading our white paper.
Learn how to optimize the analysis of your viral vectors by reading our E-book.
This paper explains how various types of light scattering can be used to characterize vaccines. By measuring several attributes including size, shape, molar mass, and other parameters derived from these fundamental characteristics, light scattering aids in vaccine discovery, development, and manufacturing.
Where high-throughput analysis and screening of biologics is concerned, Wyatt’s DynaPro Plate Reader line of in-plate dynamic light scattering instruments has become the de facto standard, relied upon by drug product development scientists across the globe for assessing developability, pre-formulation, aggregation and stability. Learn more by reading our application note.
This document lists key publications using multi-angle and dynamic light scattering for the characterization of vaccine agents such as viruses, virus-like particles, mRNA or DNA vectors, polysaccharides, and protein-polysaccharide conjugates.
AAV has mild immune response, able to deliver its payload to a wide range of host cells, and is becoming a prominent delivery vehicle in gene therapy. SEC-MALS method is presented for measuring total capsid particle concentration, relative capsid content, and percentage of monomer or aggregates.
Current methods to monitor molar mass during polysaccharide production employ off-line SEC-MALS analysis, during which a single run can take up to 30 minutes. Real-time multi-angle light scattering (RT-MALS) saves time and ensures that the process ends as soon as the endpoint criterion is achieved. Learn more in our application note.
In liposome and lipid nanoparticle (LNP) drug-delivery applications, particle size is a critical quality attribute (CQA) that impacts bioaccessibility, retention time and biodistribution. Learn more in this application note.
This document lists key publications using CG-MALS for the characterization of specific self-association in proteins and other biomacromolecules.
This document lists patents and patent applications using CG-MALS. Where patent applications have been submitted to multiple countries or organizations, only one is mentioned.