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August 17, 2019
Migration Inhibitory Factor

AN4004: Conformation of a Trimeric Protein by DLS

Learn how to characterize MIF's in our application note.

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August 17, 2019
Mixed Micelle

Measurement of Mixed Micelle Size

The size or aggregation number (N) of these micelles is an indication of their efficiency for solubilization and also correlates with the viscosities of their solutions. Learn more by reading our application note.

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August 17, 2019

WP4005: Determination of critical micelle concentration by dynamic light scattering

Learn how to characterize detergent by using light scattering by reading our application note.

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August 17, 2019
Molecule Aggregation

Non-Specific Small Molecule Aggregation

In order to develop a rapid method of detecting compound behavior, we utilized the DynaPro Plate Reader to examine the light scattering properties of a dilution series of known aggregating inhibitors. Learn more by reading our application note.

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August 17, 2019
Elastin like Polypeptides

Elastin-Like Polypeptides (ELP) Block Co-Polymers

In this application note, we studied genetically engineered polypeptides that undergo controlled self-assembly into monodisperse nanoparticulates.

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August 17, 2019
Protein Removal

Verification of Protein Aggregate Removal

The presence of aggregation in immunoglobulin biopharmaceuticals is a significant concern during all phases of drug development. Learn more by reading our application note.

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August 17, 2019
DynaPro Plate Reader

Screening High-Concentration Protein-Protein Interactions

Learn how to screen MABs by reading our application note.

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August 17, 2019
Virus-Like Particle Characterization

AN2614: Virus-like particle characterization using FFF-MALS

Learn how to characterize different VLP fractions (fragments, monomers, dimers, trimers and aggregates) by reading our application note.

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August 17, 2019
Separation of GCSF

Separation of GCSF using AF4

In this application note, we develop an Asymmetrical Flow Field Flow Fractionation (AF4) method that provides separation and quantification of the monomer’s soluble and insoluble aggregates as well as the determination of the molecular weights.

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August 17, 2019
Lipid Emulsions

Lipid Emulsions

Emulsion particle size has a profound effect on the physical properties of the emulsion, as well as on its stability. Learn more by reading our application note.

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August 17, 2019
Virus Particle Characterization

Vaccines: Virus Particle Characterization

Learn how to characterize virus particles thoroughly in terms of their size distribution, aggregation, and absolute counts-per-unit volume by reading our application note.

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August 17, 2019
Peptide Hormone

Peptide Hormone Aggregation

In this application note, a proprietary peptide hormone (MW~ 3500), was evaluated for its aggregation behavior using the Eclipse AFFF.

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Ultimate Guide

Thirteen key questions to ask when buying a Multi-Angle Light Scattering (MALS) or Dynamic Light Scattering (DLS) instrument.

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Solutions Guide

Our Solutions Guide combines Wyatt's product lines, applications and services into a single comprehensive booklet.

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Biologics Guide

Our Biologics Guide highlights tools and techniques for characterizing biologics and complex drugs.

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Instruments

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Applications

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Properties

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  • Charge & Zeta Potential
  • Interactions
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Wyatt's line of multi-angle static light scattering products couple to size exclusion chromatography (SEC-MALS), field-flow fractionation (FFF-MALS) and stop-flow composition-gradient systems (CG-MALS). Our dynamic light scattering (DLS) products operate in traditional cuvette as well as on-line and automated, high-throughput modes. We also offer unique instruments for electrophoretic light scattering (ELS), differential refractometry and differential viscosity. Wyatt Technology was acquired by Waters Corporation.

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