August 17, 2019

IgG Aggregation via Fluorescent Dye Detection

In this application note, we use size exclusion chromatography (SEC) and asymmetrical flow field flow fractionation (AF4) in combination with UV, fluorescence, and multi-angle laser light scattering (MALS) detection to quantify and characterize monoclonal antibody (IgG) aggregates in heat stressed formulations.